Although it has an unappealing appearance, Xylaria nigripes (Klotzsch) Cooke—commonly known as O Linh ginseng—holds significant medicinal value. Traditionally used in medicine, this fungus is known for its sedative effects, ability to treat insomnia, stop bleeding, lower blood pressure, and aid in various health conditions.

Additionally, Xylaria nigripes (XN) is believed to enhance memory, protect the brain, and nourish the kidneys. It is particularly beneficial for individuals recovering from surgery, postpartum mothers, and those who are breastfeeding, making it a highly regarded medicinal herb.

Belonging to the Xylariaceae family, XN has long been used in traditional medicine as a remedy for insomnia and trauma, as well as a nerve tonic. Both in vivo and in vitro studies have demonstrated its numerous bioactivities, including antioxidant, immunomodulatory, anti-inflammatory, hepatoprotective, and anti-tumor properties. It has also been shown to prevent spatial memory impairment, exhibit antidepressant effects in epileptic patients, enhance insulin sensitivity, and provide neuroprotective benefits.